Multi-Drug Resistant Infections and Antibiotic Selection

Multi-drug resistant organisms (MDROs) are one of the of most urgent health care issues of the 21st century. Bacteria are developing ways of resistance to available antibiotics quicker than we can develop new therapies. Many are calling our current situation the “post antibiotic era” for this reason. Treatment with very high powered antibiotics (often in combination) is the mainstay of therapy. Dr. Gallaher has extensive experience in managing MDROs and can provide consultative assistance for primary care physicians and treatment for their patients as well.

Common MDROs

One of the most common MDROs is methicillin-resistant staphylococcus aureus (MRSA). If left untreated, MRSA infections can enter the bloodstream, causing bacteremia, and possibly endocarditis. When treated, it often takes a long time to heal, and may require various medications to clear the infection entirely. Other common MDROs include:

  • Vancomycin resistant enterococci (VRE)
  • Extended spectrum beta lactamase Producers (ESBLs)
  • Klebsiella pneumoniae carbapenemase (KPC)
  • Resistant acinetobacter baumannii

What You Can Do

The answer here is simple: follow good hygiene practices each and every day. Not taking proper care of ourselves not only leaves us susceptible to these dangerous infections, it makes our bodies breeding grounds for bacteria. Following good oral hygiene and monitoring any cuts, scratches or open wounds is also extremely important, as they can act as open doors for bacteria to enter the body. Finally, protect yourself and those around you by staying home when you are sick. When you go to work or school when you aren't feeling well, you not only expose your already weakened immune system to other bacteria, you expose those around you to your infection.